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Core Cleanse

Core Cleanse

Core Cleanse is scientifically formulated with clean macronutrients, key phytonutrients, fiber, and alkalinizing factors to enhance Phase II liver detoxification and Phase III elimination of xenobiotics and xenoestrogens.

Use it stand alone or as part of the Remedy Reset 7 Day Detox!

  • Phase II and III Detoxification Support
  • Provides Key Alkalanizing Factors to Support Toxin Excretion
  • Supports Healthy Estrogen Detoxification
  • Promotes Gastrointestinal Health
Regular price $80.00
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Health Benefits

The CDC estimates that more than 100,000 chemicals are used by Americans and about 1,000 new chemicals are introduced annually. Evidence suggests even low-level toxicity is related to a variety of health concerns. In addition, the standard American diet, which is high in sugar and caffeine while low in nutrient density and fiber, has been shown to slow detoxification mechanisms and reduce the elimination of toxins. Therefore, it is important to have an aggressive, daily detoxification strategy that supports the various phases of detoxification.

The ingredients included in Core Cleanse were specifically chosen for their ability to support Phase II detoxification and Phase III elimination.

N-acetyl cysteine, along with glycine and taurine, are well-known amino acids that enhance liver detoxification.

The antioxidants included in Core Cleanse, such as lipoic acid, green tea, ellagic acid and a unique vegetable antioxidant blend, upregulate key Phase II enzymes and protect the liver from oxidative damage.

In addition, watercress, pomegranate and potassium citrate provide essential support for the kidneys, facilitating the efficient elimination of toxins through urinary excretion.

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N-Acetyl Cysteine

N-acetyl cysteine (NAC) is a sulfhydryl-containing amino acid that is commonly used to support liver health. NAC protects the body from oxidative damage, increases Phase II biotransformation and enhances the normal breakdown of toxins and other metabolic by-products of the body.


One of the six Phase II biotransformation pathways is amino acid conjugation (the attachment of amino acids to a toxin). Glycine is one of the amino acids used in this process, and it is also necessary for glutathione synthesis. Glycine preserves intracellular glutathione (GSH) concentration and protects cells from oxidative damage. This process is mediated by a protein called glycine transporter 1, or GLYT1.


The sulfation pathway is another important Phase II detoxification pathway. In the sulfation pathway, a sulfur containing molecule attaches to the toxin to produce a compound that can be excreted from the body.

Potassium Citrate

Potassium is an essential mineral found in many fiber-rich whole foods and is important for various functions in the body, like electrolyte and acid-base balance. Potassium citrate is a citrate salt known to help regulate urinary pH levels, promote alkalinization in the blood and make the water-soluble toxins processed from biotransformation more easily excretable via the urine by the kidney.

Pomegranate Fruit Extract

The pomegranate fruit is well known for its high antioxidant levels and ability to protect tissues from free radical damage. It has been shown that pomegranates can have up to three times more antioxidants than green tea or red wine. In addition, the specialized blend of flavonoid antioxidants in pomegranate fruit extract has been shown to enhance the activity of key detoxification enzymes while supporting and protecting kidney function to increase the elimination of toxins through urinary excretion. 

Watercress Extract

Watercress is a unique cruciferous vegetable that is a member of the cabbage family Brassicaceae. It is a nutrient-dense green plant that has been shown to boost the body’s detoxification mechanisms. 

Lipoic Acid

Lipoic acid is a potent antioxidant that has been shown to increase glutathione, vitamin E and vitamin C levels in the body. Lipoic acid has been shown to support Phase II biotransformation by increasing the activity of enzymes, including NAD(P)H, quinone reductase and glutathione S-transferase.

Green Tea Leaf Extract

Green tea is one of the most widely consumed beverages throughout the world. One of the main polyphenols in green tea includes epigallocatechin-3-gallate (EGCG). Green tea polyphenols have been shown to increase antioxidant protection. Green tea has also been shown to enhance liver detoxification.

Rosemary Leaf Extract

Rosemary includes polyphenols that are potent antioxidants. Carnosol, an antioxidant in rosemary, induces glutathione S-transferase and other important Phase II enzymes. Rosemary essential oil and carnosol have also been shown to increase GSH levels.

Vegetable Antioxidant Blend

Core Cleanse contains a blend of high-concentration superfood vegetables with significant antioxidant potential. The blend is high in ORAC value (oxygen radical absorbance capacity, a method of measuring antioxidant activity) and includes health-promoting compounds, like sulforaphane and glucosinolates. Cruciferous vegetables, including broccoli, kale and Brussels sprouts, increase the enzyme activity of both Phase I and Phase II biotransformation pathways. 

Schisandra Berry Extract

Schisandra is an adaptogenic botanical used medicinally to help fight off the physical and mental effects of stress. Schisandra is also used to support liver health and neutralize the effects of toxin exposure. Schisandra enhances liver biotransformation pathways by increasing the levels of reduced glutathione in the liver as well as glutathione reductase and glutathione S-transferase activity. 

Fiber Blend

The average recommendation for fiber intake is 25-30 g per day. Only 5% of the population meets the daily requirement. To help close the fiber intake gap and support the elimination of toxins, Core Cleanse provides a blend of diverse fibers, which includes resistant tapioca dextrin, guar gum, flaxseed flour, glucomannan, fig and prune fiber, and arabinogalactan from larch trees. This fiber blend supports a higher level of microbial richness and diversity as well as intestinal barrier function.

Suggested Use

Mix 2 scoops (39.0 g) with 8 oz. of water or the beverage of your choice two times daily or as recommended by your health care professional

14 Servings per jar.


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Dr Morgan Miller PharmD Circle

Dr. Morgan Recommends:

Core Cleanse is a part of my 7 day Remedy Reset detox program but can be used stand alone for daily nutritional support.

It tastes great , provides baseline nutrition, and supports both phase II and phase III detox pathways.